News &amp; Updates

In very elderly nonvalvular atrial fibrillation (NVAF) patients who are ineligible for standard anticoagulation, increasing levels of B-type natriuretic peptide (BNP) appear to be correlated with higher risks of stroke or systemic embolism, reports a new study.

Which canagliflozin dose is best for T2DM patients with hypertension?

A recent meta-analysis offers new proof of different canagliflozin doses for hypertension management in patients with type 2 diabetes mellitus (T2DM) complicated by hypertension. However, low-density lipoprotein cholesterol (LDL-C) and the risk of urinary tract infection must be observed.

22 May 2022

Conduction disturbances common after new-generation self-expanding valve implantation

Implantation with new-generation, self-expanding aortic valves appears to result in a significant spike in the rates of high-degree cardiac conduction disturbance, such as an increase in PR and QRS intervals, reports a new study.

Early evolocumab helps reduce LDL-C levels, prevent recurrent ischaemic cardiovascular events

In acute coronary syndrome (ACS) patients who have undergone percutaneous coronary intervention (PCI), early treatment with evolocumab as an addition to statin can lower low-density lipoprotein cholesterol (LDL-C) levels as well as reduce the incidence of recurrent ischemic cardiovascular events, while having satisfactory tolerability and safety, according to a study.

Isolated systolic hypertension tied to increased LV mass index, aortic stiffness in adolescents

Adolescents with isolated systolic hypertension (ISH), including the spurious hypertension (sHTN) subtype, show more noticeable markers of cardiac end-organ damage, higher aortic stiffness, and stroke volume than those with white-coat hypertension (WCH), a study has shown.

21 May 2022

Late nonfasting plasma glucose tied to CVD deaths

The risks of cardiovascular disease (CVD) mortality appear to be higher among adults with elevated late nonfasting plasma glucose (PG) levels independently of glycated haemoglobin (HbA1c), a recent study reports.

Stroke while on anticoagulant therapy predicts recurrence, bleeding risks

20 May 2022

Patients who have had a stroke despite being on nonvitamin K antagonist oral anticoagulant therapy are likely to experience a recurrent ischaemic stroke episode and bleeding, according to data from the RENO-EXTEND Study.

20 May 2022

Prolonged nightly fasting may do more harm than good in older adults

Habitual prolonged nightly fasting does not lead to improvements in certain cardiovascular, renal, inflammation, and nutritional status biomarkers among community-dwelling older adults, a study has found. Instead, it shows modest negative associations suggesting the potential harm of extended periods of time between meals.

High triglycerides-to-HDL-C ratio poses elevated stroke risk in people with healthy BMI

Increased triglycerides (TG)-to-high-density lipoprotein cholesterol ratio (TG/HDL-C) appears to be associated with a markedly raised risk of stroke only among individuals with healthy body mass index (BMI), according to a study.