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High-risk endometrial cancer outcomes not compromised with minimally invasive vs open surgery
In the treatment of endometrial cancer patients with high-risk histology, minimally invasive surgery neither worsens cancer prognosis nor contributes to a significant increase in the risks of recurrence and mortality as compared with open surgery, according to a systematic review and meta-analysis.

CPET a useful cardiovascular risk assessment tool for patients undergoing cancer surgery
For patients undergoing surgery for oesophageal and gastric cancer, cardiopulmonary exercise testing (CPET) appears to be a reliable predictor of major cardiovascular complications, as reported in a study.

Ribociclib–binimetinib combo safe, effective in NRAS-mutant melanoma
Treatment with the combination of ribociclib plus binimetinib appears to be well tolerated and delivers modest clinical activity in patients with locally advanced or metastatic melanoma harbouring NRAS mutation, according to the results of a phase Ib/II study.





