News & Updates

A study suggests maintaining mycophenolic acid (MPA) area under the concentration‒time curve (AUC0‒12h) ≥31.51 μg/h/mL to significantly lower the risk of relapse in paediatric patients with nephrotic syndrome (NS).

Relative renal volume (RRV) by ultrasound demonstrates accurate prediction of differential renal function in children with unilateral primary vesicoureteral reflux, reports a study.

Academic pressure may be putting adolescents at risk of depressive symptoms and, possibly, self-harm, according to new research.

High consumption of ultraprocessed food (UPF) during early childhood is associated with adverse behavioural and emotional symptoms among preschool-aged children, according to a recent study.

In children with acute nonoperative musculoskeletal injury, treatment with ibuprofen alone appears adequate for relieving pain, with the addition of acetaminophen or hydromorphone yielding no additional analgesic effect, as shown in two No OUCH randomized clinical trials.

In children with Dravet syndrome, treatment with the investigational antisense oligonucleotide zorevunersen appears safe and efficacious, with seizure frequency reductions of up to 90 percent and improvements in nonseizure symptoms, according to two phase 1–2a studies (MONARCH and ADMIRAL) and the corresponding open-label extension studies (SWALLOWTAIL and LONGWING).

In adolescents with well-controlled HIV, switching from an oral antiretroviral therapy (ART) regimen to the long-acting injectable cabotegravir plus rilpivirine combination appears to be not only safe and efficacious in maintaining viral suppression but also strongly favoured, according to the end-of-study data from the phase I/II IMPAACT 2017 study.

An artificial intelligence (AI)-assisted dietary recording application (app) demonstrates its potential as an alternative to expert evaluation for nutritional management in young patients with anorexia nervosa (AN), according to a study.