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Breast cancer also a male problem
In Malaysia, breast, colorectal, and lung cancers account for approximately half of all reported cancer cases. In order of prevalence, breast cancer tops the list, followed by colorectal, lung, nasopharyngeal, and liver cancers. [Available at https://gco.iarc.fr/today/data/factsheets/populations/458-malaysia-fact-sheets.pdf Accessed on 27 October 2022]
Capivasertib + fulvestrant boosts PFS in AI-resistant HR+/HER2– advanced breast cancer
The AKT inhibitor capivasertib, when added to fulvestrant, doubled progression-free survival (PFS) in patients with aromatase inhibitor (AI)-resistant hormone receptor-positive (HR+)/HER2*-negative (HER2–) advanced breast cancer (ABC), results of the phase III CAPItello-291 trial showed.
Adagrasib shows antitumour activity in KRAS G12C-mutant colorectal cancer
Adagrasib appears to have some effect against metastatic, KRAS G12C-mutated colorectal cancer when used in treatment-experienced patients either as oral monotherapy or in combination with cetuximab, according to the results of a phase I-II, open-label study.
Repeat transurethral resection of bladder tumour predicts but does not improve survival
Repeat transurethral resection of bladder tumour prior to radical cystectomy, regardless of whether or not neoadjuvant chemotherapy is administered, does not seem to improve survival in patients with muscle-invasive bladder cancer, reveals a recent study.