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Metabolic dysfunction-associated fatty liver disease ups risk of severe COVID-19
Metabolic dysfunction-associated fatty liver disease (MAFLD) can escalate the incidence of severe COVID-19, but no association between MAFLD and COVID-19 death has been confirmed, suggest the results of a meta-analysis.

Maintenance with ABC/3TC + RPV sustains virological suppression in HIV-1
Switching to abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) for maintenance therapy is a safe and effective option for patients with virologically suppressed HIV-1, according to a recent Singapore study.

NLR a stronger predictor of COVID-19 outcomes than RSV, influenza
The neutrophil-to-lymphocyte ratio (NLR) appears to have stronger prognostic value for the coronavirus disease 2019 (COVID-19) than for influenza and the respiratory syncytial virus (RSV), a recent study has found.

IL-6 receptor antagonists benefit COVID-19 patients with high baseline death risk
Interleukin (IL-6) receptor antagonists provide significant clinical benefit in coronavirus disease 2019 (COVID-19) patients with high baseline mortality risk, a recent study has found. In contrast, such agents pose considerable threat when baseline mortality risk is low.

COVID-19 pandemic has shortened life expectancy in 2020: study
Life expectancy has decreased during the COVID-19 pandemic, with more than 28 million excess life years of life lost in 2020 in 31 countries, according to a study, noting a higher rate in men than women.

SG’s COVID-19 lockdown takes toll on older adults’ mental, financial wellbeing
During Singapore’s coronavirus disease 2019 (COVID-19) lockdown, older adults experienced a decrease in depressive symptoms accompanied by growing feelings of loneliness and lower physical activity (PA), according to a recent study.

