News & Updates

Among patients with epilepsy in Singapore, those who use multiple antiseizure medications (ASMs) face a substantial burden of hospitalization, according to a study.

Good adherence to medications contributes to a reduced risk of death in adults with chronic disease, while non-adherence may increase such risk by up to 45 percent, reports a South Africa study.

Anticholinergic burden (ACB) is significantly associated with sleep disorders among people living with HIV, according to a study.

Dietary iron intake appears to have a U-shaped association with the risk of gastric cancer, as suggested in a case–control study.

Cardiovascular disease (CVD), diabetes, and chronic kidney disease (CKD) coexist across patient populations, driven by rising obesity rates and unhealthy lifestyle patterns. The cardio-kidney-metabolic (CKM) framework highlight show these conditions are not isolated entities but a continuous, interlinked spectrum. Within this continuum, obesity represents the starting point, which is the earliest and most modifiable point of intervention. In this instalment of the CKM cardiology series, Dato’ Sri Dr Azhari Rosman discusses why obesity must be recognised and treated early as a chronic disease, how neurohormonal and behavioural mechanisms reinforce weight gain, and why modern anti-obesity pharmacotherapies, particularly glucagon-like peptide 1 receptor agonists (GLP-1 RAs), are reshaping and influencing preventive cardiology.

Osteoarthritis (OA) is the most prevalent form of arthritis, mostly affecting individuals >40years old. OA frequently involves weight-bearing joints such as the knees, hips, lower back, and cervical spine. The primary aetiologies are ageing—where cumulative mechanical wear accelerates cartilage decline—and obesity, which increases joint load. Other contributing factors include joint malformations, genetic defects in cartilage, and prior injuries.

New research suggests that moderate intake levels of caffeinated coffee and tea may reduce the risk of dementia and produce modest improvements in cognitive function.

A recent study has found that employment in managerial and professional positions across early and mid-adulthood may result in a reduced risk for lower urinary tract symptoms (LUTS) at midlife, while that in service positions tends to increase such risk.