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Does diabetes worsen survival in metastatic breast cancer?
Diabetes does not appear to increase mortality in patients with metastatic breast cancer (MBC), but diabetes and hyperglycaemia both contribute to worse overall survival (OS) in a cohort of longer-term survivors, a study has found.

SGLT2 inhibitors help prevent new-onset AF in diabetic Asians
Use of sodium-glucose cotransporter 2 inhibitors (SGLT2is) may reduce the risk of new-onset atrial fibrillation (AF) relative to glucagon-like peptide-1 receptor agonists (GLP-1RAs) in Asian patients with type 2 diabetes mellitus (T2DM) in a real-world practice, reports a recent study.

COVID-19 lockdown weakens metabolism in people with glucose intolerance
In Japan, the declaration of a state of emergency in response to the COVID-19 pandemic led to negative metabolic consequences in people with glucose intolerance, such as lowered skeletal muscle and increased body weight and body fat, a recent study has found.

Insulin glargine, degludec yield comparable effects on glycaemic control
In patients with of type 2 diabetes (T2D), glargine 300 U/mL (Gla-300) and degludec 100 U/mL (Deg-100) deliver similar improvements in glycaemic control, without increasing weight and hypoglycaemic events over 6 months of treatment, according to data from the retrospective RESTORE-2 NAIVE study.

Semaglutide lowers stroke risk in type 2 diabetes with high CV risk
A post hoc analysis of the SUSTAIN 6 and PIONEER 6 trials has found that semaglutide reduces incidence of any stroke in people with type 2 diabetes (T2D) at high cardiovascular (CV) risk vs placebo.



