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Breakthrough infections with COVID-19 Delta variant linked to lower memory B cell response
The memory B cell response appears to be weaker in vaccinated individuals who develop breakthrough infections with the Delta variant of the coronavirus disease 2019 (COVID-19), according to a new Singapore study.
Fulvestrant-palbociclib combo pre-progression improves PFS in ESR1+ mBC
Switching to a fulvestrant-palbociclib regimen prior to disease progression after detection of elevated ESR1 mutations in the blood of patients with hormone receptor-positive (HR+), HER2-negative (HER2-) metastatic breast cancer (mBC) who were receiving aromatase inhibitors (AIs) plus palbociclib extended their progression-free survival (PFS), results of the phase III PADA-1 trial showed.
More than 1 in 4 young adults test seropositive for COVID-19
A recent study has shown that more than a quarter of young adults are seropositive for SARS-CoV-2, many of whom show single positivity with IgM. Such seropositivity was higher among those who had cases of the coronavirus disease 2019 (COVID-19) in the household and those who used public transport.
