News & Updates

Reduced endometrial thickness contributes to a dramatic decrease in the chance of live birth following embryo transfers, a study reports. In contrast, live birth rates markedly improve with thicker endometrium.

Polymyxin B-associated nephrotoxicity is still a major concern in China, with the use of polymyxin B loading doses and the combined use of multiple nephrotoxic drugs independently adding to an increased risk of acute kidney injury (AKI), a study has found.

Among inflammatory bowel disease (IBD) patients, the discontinuation of immunomodulator treatment does not contribute to the risk of loss of response although it may lead to an increase in antidrug antibodies, according to a study.

In the management of women with polycystic ovary syndrome (PCOS), metformin at various therapeutic doses appears to reduce body weight, body mass index, and waist circumference when compared with placebo, sitagliptin, and acarbose, according to the results of a meta-analysis. On the other hand, pioglitazone and rosiglitazone contribute to an increase in all three outcomes.

At a dose of 6 mg, brolucizumab yields substantial visual gains and anatomical improvements in patients with diabetic macular oedema without increasing the risk of serious adverse ocular events when compared with aflibercept, according to data from two phase III trials.