News & Updates

In the treatment of patients with acute, intermediate-risk pulmonary embolism (PE), administering ultrasound-facilitated, catheter-directed thrombolysis (USCDT) on top of anticoagulation results in better short-term outcomes compared with anticoagulation alone, as shown in the multinational, adaptive-design, open-label HI-PEITHO trial.

The first-in-class KRAS G12D–targeted protein degrader setidegrasib has demonstrated antitumour activity in patients with previously treated advanced non–small-cell lung cancer (NSCLC) or pancreatic ductal adenocarcinoma harbouring the KRAS G12D mutation, according to a phase I study.

In patients with fibrotic interstitial lung disease (ILD), the severity of cough appears to be worse in the presence of gastroesophageal reflux disease (GERD), according to a retrospective study.

Oxygen therapy delivered through a high-flow nasal cannula does not appear to significantly lower mortality compared with standard oxygen therapy in patients with hypoxemic respiratory failure, according to an open-label trial.

Among patients receiving immune checkpoint inhibitors (ICIs), those with interstitial lung disease (ILD) have a significantly greater risk of developing checkpoint inhibitor pneumonitis (CIP) and may experience worse outcomes, including recurrence and death, reveals a study.

Singapore is seeing a shift in the incidence of lung cancer, with rising cases among women, including those who are younger and nonsmokers, according to local research.

People who wish to quit vaping may find success with the help of varenicline, which has been found in a recent study to result in numerically higher abstinence rates relative to placebo.