News & Updates

Treatment-resistant depression (TRD), defined as treatment failure following ≥2 trials of antidepressants at adequate doses, duration and adherence, is associated with a greater risk of all-cause mortality and higher healthcare costs, according to a population-based cohort study by the University of Hong Kong (HKU), Chinese University of Hong Kong, London School of Economics and Political Science and University College London.

A novel gut microbiota–derived synbiotic formula known as SIM01 is an effective adjuvant therapy for coronavirus disease 2019 (COVID-19), which hastens antibody formation against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), reduces nasopharyngeal viral load, reduces proinflammatory immune markers, and restores gut dysbiosis in COVID-19 patients, researchers from the Chinese University of Hong Kong (CUHK) have reported.

Recurrent implantation failure (RIF) refers to the failure to achieve a clinical pregnancy after three in vitro fertilization (IVF) attempts with at least four good-quality embryos. RIF leaves couples frustrated and desperate for answers and is challenging for clinicians to handle, compounded by the impact of the COVID-19 pandemic restrictions. Two experts, Dr Ameet Patki, Medical Director of Fertility Associates Mumbai and Hon Assoc Prof at KJ Somaiya Medical College & Hospital, India, and Dr Prakash Mayandi, Metro IVF Fertility Centre, Kuala Lumpur, Malaysia, weigh in with their views on managing RIF during the COVID-19 pandemic.

For women with obesity and unexplained infertility, weight loss can result in improved cardiometabolic health. This benefit, however, does not translate to better pregnancy outcomes.