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Chloride-potassium assessment helps diagnose thiazide-associated hyponatraemia
Assessment of apparent strong ion difference (aSID), potassium, and chloride in urine is a useful tool for classifying patients with volume-depleted thiazide-associated hyponatraemia (TAH) requiring fluid substitution relative to those with syndrome of inappropriate antidiuresis (SIAD)-like presentation warranting fluid restriction, according to a recent study.

Triple G agonist shows therapeutic potential in obesity
Treatment with retatrutide, the novel agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and glucagon receptors, leads to marked reductions in body weight in individuals with obesity, as shown in the results of a phase II trial.

Female sex protective against obesity-driven dysregulation of glucose metabolism
Insulin sensitivity and secretion differ by sex among Asians without diabetes, reveals a study, noting that female sex is protective on obesity-driven dysregulation of glucose metabolism.





