News &amp; Updates

Patients who have had a stroke despite being on nonvitamin K antagonist oral anticoagulant therapy are likely to experience a recurrent ischaemic stroke episode and bleeding, according to data from the RENO-EXTEND Study.

20 May 2022

Once-daily, low-dose elagolix reduces HMB in premenopausal women with uterine fibroids

20 May 2022 by

Once-daily (QD) administration of low-dose elagolix 150 mg led to significantly reduced heavy menstrual bleeding (HMB) in premenopausal women with uterine fibroids, according to a study presented at ACOG 2022.

Multi-day not better than single-day antibiotic at preventing UTI after BTX shot

Prophylactic antibiotic works to prevent the development of urinary tract infection (UTI) following intravesical OnabotulinumtoxinA (BTX) injection, with a multiple-day regimen being as effective as a single-day regimen, according to a study.

Sustained benefits with ocrelizumab in relapsing-remitting MS

Patients with relapsing-remitting multiple sclerosis (RRMS) who have suboptimal response to disease-modifying therapies (DMTs) experienced low disease activity after switching to ocrelizumab, according to interim results of the LIBERTO study.

19 May 2022

Nasal microbiome predicts bronchopulmonary dysplasia in preterm infants

In infants born preterm, the nasal microbiome seems to correlate with the incidence and severity of bronchopulmonary dysplasia, reports a recent study.

COVID boosters: Where from here?

Having a fourth dose of COVID-19 vaccine (ie, second booster dose) substantially protects against severe illness in face of the Omicron variant, compared with only three doses of vaccine that were given more than 4 months earlier, according to data from the Israeli Ministry of Health database.

Oocyte microinjection device allows more efficient intracytoplasmic sperm injection

A group of Australia-based researchers has developed a novel device that makes intracytoplasmic sperm injection (ICSI) a less technically demanding procedure, reducing dependence on the experience level of embryologists and, in turn, dramatically improving fertilization success.

Tofacitinib on par with TNFi in rheumatoid arthritis

Tofacitinib demonstrates similar physician- and patient-reported effectiveness to tumour necrosis factor inhibitors (TNFi) in rheumatoid arthritis (RA), according to a study.

19 May 2022

5-strain probiotic blend improves functional gastrointestinal symptoms

Treatment with a newly developed probiotic blend made up of five strains (Bl-04, Bi-07, HN019, NCFM, and Lpc-37) is safe and leads to better gastrointestinal (GI) well-being as early as day 14, with sustained improvements up to day 30, a recent study has shown. Few adverse events resulting in discontinuation have been reported.

Prolonged nightly fasting may do more harm than good in older adults

Habitual prolonged nightly fasting does not lead to improvements in certain cardiovascular, renal, inflammation, and nutritional status biomarkers among community-dwelling older adults, a study has found. Instead, it shows modest negative associations suggesting the potential harm of extended periods of time between meals.