News &amp; Updates

Upadacitinib treatment for atopic dermatitis (AD) may cause acne as a side effect, though this is usually only mild or moderate in severity and can be managed by topical intervention, reports a recent study.

23 Jun 2022

Appendectomy carries modest risk of microscopic colitis

Undergoing appendectomy may put patients at risk of developing subsequent microscopic colitis, although the risk increase appears to be modest, as shown in a study.

Premature menopause poses increased mortality risk

While affecting only a small group of women, premature ovarian insufficiency appears to have a negative effect on mortality, according to a study.

HF risk: Time to rethink alcohol limits?

A moderate to high intake of alcohol appears to increase the risk of heart failure (HF) progression in individuals with pre-HF, according to a study presented at Heart Failure 2022.

22 Jun 2022

High omega-3 fatty acids tied to better sleep

Higher serum levels of long-chain omega-3 fatty acids are significantly correlated with healthy sleep among adults, reports a recent US study.

Add-on brivaracetam safe, cuts focal seizure frequency

Adjunctive therapy with brivaracetam is well tolerated and yields substantial reduction in focal seizure frequency regardless of the number or type of concomitant antiseizure medications used, as reported in a study.

Depression, sleep disturbance tied to urinary symptoms in men with LUTS

In men with lower urinary tract symptoms (LUTS), urinary symptom subdomains show an independent association with modifiable clinical variables such as sleep quality and depression at all time points, a study has found. However, these variables do not predict the degree of improvement in LUTS after assessment and treatment over the medium term.

22 Jun 2022

Late-afternoon intake of high-energy supplements may do more harm than good in women

Women with lower body mass index (BMI) who consume high-energy oral nutritional supplements (ONS) late in the afternoon experience only a partial and short-lived energy intake suppression, which increases their total energy intake but has a harmful effect on measures of insulin sensitivity, results of a study have shown.

Aminosalicylate use more common among older than younger IBD patients

Use of medication is markedly different among older patients with inflammatory bowel disease (IBD), with more aminosalicylate monotherapy and less antitumour necrosis factor monotherapy than younger patients, according to a US study.

22 Jun 2022

Dostarlimab in rectal cancer: are we inching towards a cure?

In what has been dubbed as ‘a small but mighty study’ at ASCO 2022, a phase II trial spearheaded by investigators from Memorial Sloan Kettering Cancer Center in New York, US heralded the remarkable efficacy and safety of the monoclonal antibody dostarlimab for the treatment of locally advanced mismatch repair-deficient (dMMR) rectal cancer.