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Stopping RAS inhibitors does not slow eGFR decline in advanced CKD

16 Dec 2022 by

In patients with advanced chronic kidney disease (CKD), discontinuing renin–angiotensin system (RAS) inhibitor therapy does not slow down decline in estimated glomerular filtration rate (eGFR), a recent trial showed.

16 Dec 2022

Food interrupts absorption of diazepam nasal spray

15 Dec 2022

Food appears to affect the pharmacokinetics of diazepam dosed via nasal spray, with absorption being markedly decreased and delayed, according to an open-label crossover study.

15 Dec 2022

Restorative hearing aids may help stave off cognitive decline in those with hearing loss

14 Dec 2022 by

Restorative hearing devices may help stave off the risk of cognitive decline in patients with hearing loss, according to a systematic review and meta-analysis of 31 studies.

14 Dec 2022

Low-dose polypill: Another step forward in hypertension management?

12 Dec 2022 by

A polypill comprising ultra-low doses of four antihypertensive drugs shows promise in reducing blood pressure (BP) levels compared with standard monotherapy, according to a small study presented at AHA 2022.

12 Dec 2022

Edaravone confers neuroprotection in stroke patients

10 Dec 2022

Edaravone appears to be safe and effective in the treatment of patients with ischaemic stroke, yielding improvements in activities of daily living and neurologic deficits in the short term, a study has found.

10 Dec 2022

Depressive symptoms worsen cognition, gait, comorbidities in older adults

10 Dec 2022

Among older adults, depressive symptoms aggravate the worsening of cognition, gait speed, and other comorbidities on disability, a recent study has found.

10 Dec 2022

Minimally invasive surgery safer but less effective than open surgery in children with DRE

07 Dec 2022

In the treatment of children with drug-resistant epilepsy (DRE), minimally invasive magnetic resonance-guided laser interstitial thermal therapy is associated with lower rate of seizure freedom at 1 year but has the advantage of lower complication rates and shorter hospitalization as compared with open surgery, as shown in a study.

07 Dec 2022

Erenumab works well in chronic migraine patients across Asia

06 Dec 2022 by

Erenumab proves to be effective at lowering the number of monthly migraine days in Asian patients with chronic migraine while having a favourable safety profile, according to the results of DRAGON study.