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Latest glucose-lowering drug use and glycaemic outcome trends in HK
A retrospective cross-sectional analysis of trends in glucose-lowering drug (GLD) use and glycaemic outcomes among Hong Kong’s 0.9 million adults with diabetes between 2002 and 2019 finds a levelling off in improvements since 2014.
RYGB in severe obesity leads to weight loss, hypertension remission
In patients with severe obesity, undergoing either laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (RYGB) resulted in weight loss, according to long-term follow-up of the SLEEVEPASS* trial. However, remission of hypertension was more likely in patients who underwent RYGB compared with LSG.
Combined oral contraceptives and VTE: Which pill conveys the highest risk in young women?
Combined oral contraceptives (COCs) that contain gestodene confer a fivefold increased risk of venous thromboembolism (VTE) in young women as compared with those that contain levonorgestrel and the lowest doses of ethinylestradiol, as shown in a study.
Obese, postmenopausal women on proinflammatory diet at highest risk of breast cancer
A recent meta-analysis has confirmed the association of a proinflammatory diet with an increased risk of breast cancer, particularly among women who are obese, postmenopausal, and living in developing countries.
Add-on pembrolizumab–tocilizumab combo reduces hospitalization period in severe COVID-19
In the treatment of patients with severe COVID-19, adding the combination of pembrolizumab plus tocilizumab to standard of care (SOC) appears to result in higher and faster discharge from the hospital without sequelae, as shown in the proof-of-concept phase II COPERNICO trial.