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Polypill strategy triumphs in reducing MACE post-MI
A polypill comprising aspirin, ramipril, and atorvastatin, significantly reduced the incidence of major adverse cardiovascular (CV) events in patents with a recent myocardial infarction (MI), according to results of a phase III trial presented at ESC 2022.

High-dose iron infusion corrects deficiency, maintains iron stores in pregnancy
A single 1,000-mg infusion of ferric carboxymaltose (FCM) effectively resolves iron deficiency in pregnancy, preserving iron stores and reducing the need for repeat infusions as compared with the lower FCM dose, as shown in a study.

3D-printed masks a good alternative to N95 respirators
Reusable 3D-printed respirators offer a cost-effective alternative to N95 masks in providing protection against respiratory pathogens, such as SARS-CoV-2, suggests a recent study. In addition, fit testing results show that some 3D-printed mask designs appear to exceed the fit of N95 masks.

Bladder-directed heated chemotherapy of no clear benefit in NMIBC
In patients with intermediate-risk nonmuscle-invasive bladder cancer (NMIBC), intravesical chemohyperthermia (CHT) does not translate to better cancer control than standard room-temperature chemotherapy, according to a recent phase II study HIVEC-II.

Add-on pyrotinib in neoadjuvant setting safe, effective for HER2-positive advanced breast cancer
In the treatment of patients with HER2-positive locally advanced breast cancer, adding pyrotinib to trastuzumab plus chemotherapy in the neoadjuvant setting yields high response rates while being safe, according to the results of NeoATP trial.




