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Long-term treatment with an oral testosterone undecanoate (TU) formulation improves clinical outcomes in men with hypogonadism with no serious safety concerns, a study has shown.
Targeted oral naltrexone results in a significant reduction in drinking outcomes among sexual and gender minority men (SGM) with mild to moderate alcohol use disorder (AUD) during treatment, reports a study. This beneficial effect persists up to 6 months post-treatment.
There appears to be no significant association between serum uric acid (SUA) and major depressive disorder (MDD), suggest the results of a meta-analysis and two-sample bidirectional Mendelian randomization (MR) study.
In individuals with Wilson disease (WD), a rare disease of copper metabolism, ALXN1840 led to significantly greater copper mobilization compared with standard of care (SoC), findings from a rater-blinded phase III study have shown.
Individuals who have received one or two doses of the COVID-19 vaccinations experience improved mental wellbeing during the pandemic, reports a recent Japan study.
Treatment with upadacitinib appears to produce improvements in ulcerative colitis (UC) symptoms as early as day 1, as shown in a recent study.
In cancer patients, the presence of diabetes appears to aggravate the likelihood of developing a secondary malignancy or death, reports a recent Japan study.
In a cohort of middle-aged individuals from South Korea, the initial weight loss at 4 years appears to contribute to an increased risk of major adverse cardiovascular events (MACEs), which may be explained by residual cardiovascular burden, according to a study. However, the risk increase disappears among individuals with sustained weight loss ≥ 6 years.
Treatments used in rheumatoid arthritis, called disease-modifying antirheumatic drugs, can also lower the risk of heart disease among patients, as shown in a recent study.
Adults who adhere to a Mediterranean diet (MedDiet) achieve a small but significant increase in bone mineral density (BMD) at the lumbar spine, femoral neck, hip, trochanter, and whole body, a recent study has shown.
