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Nutritional supplementation promotes healthy weight gain in offspring

Nutritional supplementation promotes healthy weight gain in offspring

Taking nutritional supplements before and throughout pregnancy puts children at lower risk of rapid weight gain and high body mass index, according to data from the NiPPeR trial.

Excess CVD risk found in women with endometriosis

Excess CVD risk found in women with endometriosis

Endometriosis appears to be associated with a significantly elevated risk of cardiovascular disease (CVD), specifically ischaemic heart disease and cerebrovascular disease, as suggested in a study.

17 Apr 2023

A win for gemcitabine plus cisplatin and intensity-modulated radiotherapy in vulvar cancer

A win for gemcitabine plus cisplatin and intensity-modulated radiotherapy in vulvar cancer

A win for gemcitabine plus cisplatin and intensity-modulated radiotherapy in vulvar cancer

The use of gemcitabine concurrently with cisplatin and intensity-modulated radiation therapy appears to improve response and prolong progression-free survival in women with locally advanced vulvar cancer not amenable to surgical resection, according to the results of the phase II NRG Oncology Trial 279 (NRG-GOG-0279) presented at SGO 2023.

NSAID use ups risk of heart failure in T2DM patients

NSAID use ups risk of heart failure in T2DM patients

Use of nonsteroidal anti-inflammatory drugs (NSAIDs) tends to elevate the risk of first-time hospitalization for heart failure (HF) in patients with type 2 diabetes mellitus (T2DM), a study has shown. In addition, those with advanced age, elevated haemoglobin (Hb) A1c levels, and new users are particularly at higher risk.

17 Apr 2023

Fosfomycin, cefixime prevent infections in prostate biopsy

Fosfomycin, cefixime prevent infections in prostate biopsy

In patients undergoing transrectal ultrasound-guided prostate biopsy, prophylaxis with either fosfomycin or cefixime leads to fewer infectious complications, as shown in a study presented at the 38th Annual EAU Congress (EAU 2023).

Ketamine abuse may lead to LUTS, sexual dysfunction

Ketamine abuse may lead to LUTS, sexual dysfunction

Excessive use of ketamine appears to result in lower urinary tract symptoms (LUTS) and female sexual dysfunction (FSD), suggests a recent study.

Investigational imaging agent holds promise for diagnosing renal cancer

Investigational imaging agent holds promise for diagnosing renal cancer

In the pivotal phase III ZIRCON study, PET/CT imaging with ⁸⁹Zr-DFO-girentuximab, an investigational imaging agent, demonstrated potential in the noninvasive identification of clear-cell renal cell carcinoma (ccRCC) in patients with indeterminate renal masses (IDRM).

17 Apr 2023

Add-on immunotherapy improves PFS in 1L advanced or recurrent endometrial cancer

Add-on immunotherapy improves PFS in 1L advanced or recurrent endometrial cancer

Adding dostarlimab or pembrolizumab to standard first-line (1L) chemotherapy significantly improves progression-free survival (PFS) in patients with advanced or recurrent endometrial cancer, two phase III trials have shown.

17 Apr 2023

No link between nut consumption and prostate cancer

No link between nut consumption and prostate cancer

Eating nuts may not be beneficial in terms of reducing the risk of total, advanced, nonadvanced, and fatal prostate cancer, according to the results of a meta-analysis.

17 Apr 2023

Idecabtagene vicleucel boosts PFS and responses vs standard regimens in triple class–exposed R/R MM

Idecabtagene vicleucel boosts PFS and responses vs standard regimens in triple class–exposed R/R MM

Idecabtagene vicleucel (ide-cel), a B-cell maturation antigen–directed chimeric antigen receptor (CAR) T-cell therapy, improves progression-free survival (PFS) and responses vs standard regimens in patients with triple class–exposed relapsed and refractory multiple myeloma (R/R MM), the phase III KarMMa-3 trial has shown.

17 Apr 2023

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