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COVID-19 ups risk of pulmonary fibrosis

09 Nov 2023 by

Infection with COVID-19 may increase the risk of pulmonary fibrosis, and patients with a severe disease are at greater risk of developing this complication, suggests a recent study.

09 Nov 2023

LIPI score predicts survival in NSCLC patients treated with PD-1/PD-L1 inhibitor plus chemo

08 Nov 2023

Use of the lung immune prognostic index (LIPI) score can help predict the efficacy of combination therapy of programmed cell death (PD)-1/PD-ligand 1 (PD-L1) blockade and chemotherapy (CT) in patients with advanced nonsmall cell lung cancer (NSCLC), suggests a study.

08 Nov 2023

Neoadjuvant immunotherapy delivers better response in NSCLC

08 Nov 2023 by

Patients with nonsmall cell lung cancer (NSCLC) who have been treated with neoadjuvant immunotherapy show greater response than those treated with neoadjuvant chemotherapy (CT), as shown in a study. Treatment-related adverse events (TRAEs) are similar between the two groups.

08 Nov 2023

Original New Drug Application Approvals by US FDA (16-31 October 2023)

08 Nov 2023

New drug applications approved by US FDA as of 16-31 October 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

08 Nov 2023

Amivantamab-lazertinib bests osimertinib in head-to-head trial on lung cancer

08 Nov 2023 by

In the phase III MARIPOSA trial, the amivantamab-lazertinib cocktail outdid osimertinib as first-line (1L) treatment for EGFR-mutated, advanced non-small cell lung cancer (NSCLC).

08 Nov 2023

Nirmatrelvir-ritonavir benefits persist against COVID

07 Nov 2023 by

Management of most adults with COVID-19, particularly those with mild-to-moderate disease, is increasingly occurring in the outpatient setting due to the availability of effective treatment options.

07 Nov 2023

Depression severity tied to respiratory symptoms

05 Nov 2023

Depression levels among adults appear to be positively associated with respiratory symptoms, asthma, and chronic obstructive pulmonary disease (COPD), according to a study.

05 Nov 2023

Higher nasal CPAP helps avoid extubation failure in extremely preterm infants

02 Nov 2023

Extubation with higher levels of nasal continuous positive airway pressure (nCPAP) in preterm infants leads to a lower incidence of extubation failure compared with standard nCPAP levels, without compromising safety, according to a study.

02 Nov 2023

Ritonavir-boosted nirmatrelvir protects older adults against post-COVID conditions

26 Oct 2023 by

Treatment with nirmatrelvir/ritonavir helps lower the incidence of post-COVID conditions (PCC) in older adults, according to a large study.

26 Oct 2023

Older age, comorbidities drivers of hospitalization for RSV

25 Oct 2023 by

Advanced age (≥65 years) and comorbidities increase the risk of respiratory syncytial virus (RSV)-associated hospitalization, according to a presentation at IDWeek 2023.

25 Oct 2023

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COVID-19 ups risk of pulmonary fibrosis

LIPI score predicts survival in NSCLC patients treated with PD-1/PD-L1 inhibitor plus chemo

Neoadjuvant immunotherapy delivers better response in NSCLC

Original New Drug Application Approvals by US FDA (16-31 October 2023)

Amivantamab-lazertinib bests osimertinib in head-to-head trial on lung cancer

Nirmatrelvir-ritonavir benefits persist against COVID

Depression severity tied to respiratory symptoms

Higher nasal CPAP helps avoid extubation failure in extremely preterm infants

Ritonavir-boosted nirmatrelvir protects older adults against post-COVID conditions

Older age, comorbidities drivers of hospitalization for RSV