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High flow nasal oxygen feasible in pulmonary rehabilitation of COPD patients
Use of high flow nasal oxygen (HFO) is feasible during early pulmonary rehabilitation for improving exercise capacity in chronic obstructive pulmonary disease (COPD) patients after an exacerbation, results of a pilot randomized controlled trial (RCT) have shown. Additionally, HFO has high patient acceptability.

NPAR, NLR predict risk of death in COPD patients
Increased neutrophil-percentage-to-albumin ratio (NPAR) and neutrophil-to-lymphocyte ratio (NLR) appear predictive of mortality risks in community-dwelling adults with chronic obstructive pulmonary disease (COPD), suggests a US study.

BPaLM regimen continues to show benefit against rifampicin-resistant tuberculosis
In the treatment of patients with rifampicin-resistant tuberculosis, a 6-month oral regimen consisting of bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaLM) is safe and efficacious and compares favourably with standard of care, as shown in the final data from the phase IIB-III TB-PRACTECAL study.

Benralizumab appears superior to mepolizumab in severe eosinophilic asthma
Both mepolizumab and benralizumab are effective in improving the clinical outcomes of patients with severe eosinophilic asthma, as shown in a recent study. However, treatment with benralizumab appears to be better than mepolizumab in reducing exacerbations, improving forced expiratory volume, and depleting blood eosinophils.




