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Timing of liquid LT4 intake doesn’t impact bioavailability
Bioavailability studies presented at ENDO 2022 showed that patients with hypothyroidism can safely take the liquid formulations of levothyroxine (LT4) 15 or 30 minutes before meals, without having to worry about food effect on bioavailability.

Thyroid hormone sensitivity tied to advanced liver fibrosis in NAFLD
In euthyroid patients with nonalcoholic fatty liver disease (NAFLD), higher values of thyroid hormone sensitivity markers, such as the thyroid-stimulating hormone (TSH) index (TSHI) and thyroid feedback quantile-based index (TFQI), appear to aggravate the risk of advanced fibrosis, a recent study has found.

Parathyroidectomy effective for primary hyperparathyroidism regardless of localization technique
Parathyroidectomy yields excellent surgical outcomes in patients with primary hyperparathyroidism (PHPT), whether or not intraoperative localization technique (IOLT) or intraoperative parathyroid hormone (IOPTH) monitoring have been used, reports a recent study.

Neutrophils release more cytokines in DM, HFpEF patients
In patients with type 2 diabetes mellitus (DM) or heart failure with preserved ejection fraction (HFpEF), neutrophils seem to secrete more cytokines, contributing to low-grade chronic inflammation, a recent study reports.

Growth hormone reduces liver fat, fibro-inflammation in obese/overweight adults with NAFLD
In adults with overweight/obesity and nonalcoholic fatty liver disease (NAFLD), daily administration of growth hormone (GH) reduced hepatic steatosis and improved markers of hepatic inflammation and fibrosis, a study has shown.




