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Antiretroviral therapy with INSTI maintains low switch rates among people with HIV
Persons living with HIV (PLWH) often switch from first-line antiretroviral therapies (ART) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) or protease inhibitors (PI) to second-line integrase strand transfer inhibitors (INSTI), a recent Japan study has found. PLWHs tend to stay on INSTIs for a long time thereafter.

Risk downgrade common in GGG3 prostate cancer patients with single positive biopsy core
In Gleason grade group (GGG) 3 prostate cancer patients with a single intermediate-risk positive biopsy core, risk downgrading appears to be more likely than upgrading, reports a new study.

Recurrent node-positive breast cancer reveals distant metastasis in patients
Distant metastasis is present in all patients with node-positive breast cancer (NPBC) at the time of recurrence, reveals a study. Compared with diffusely metastatic (DM) patients, those with oligometastasis (OM) have shorter time to recurrence but longer overall survival (OS).






