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SG: COPD severity a key factor when choosing between therapies
Chronic obstructive pulmonary disease (COPD) patients initiating treatment with a long-acting muscarinic antagonist (LAMA) plus a long-acting β2-agonist (LABA) tend to have higher disease severity than those who are started on LAMA, according to real-world data from Singapore. However, there are as many patients who experience clinical worsening in the LAMA group as there are in the LAMA+LABA group.

40 COVID-19 vaccines and counting: Do we still need more?
There are currently 40 approved vaccines against COVID-19, of which 11 have been granted Emergency Use Authorization by the World Health Organization. [covid19.trackvaccines.org/vaccines/approved] With over 300 other candidates in the development pipeline – over 100 of which are in clinical testing [vac-lshtm.shinyapps.io/ncov_vaccine_landscape] – are new vaccines necessary?

Older age, lower BMI, seropositivity tied to RA-related bronchiectasis
Isolated bronchiectasis (BR) in rheumatoid arthritis (RA) that is not caused by interstitial lung disease (ILD) is associated with seropositivity, older age at RA diagnosis, and lower body mass index (BMI) at RA onset, a recent study has found.

OSA prevalence similar between resistant, refractory hypertension
The prevalence of obstructive sleep apnoea (OSA) is similar between resistant and refractory hypertensive patients, a study has shown. However, those with refractory hypertension are usually younger and have a better sleep pattern.





