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Shorter treatment regimen feasible for rifampin-resistant TB?

13 Feb 2023 by

Individuals with rifampin-resistant tuberculosis (RR-TB) may have the option to undergo shorter treatment periods, as findings from the phase II/III TB-PRACTECAL* trial show the noninferiority and superiority of a 24-week, all-oral regimen to standard of care (SoC). It also had a better safety profile than SoC.

13 Feb 2023

Children, older adults bear brunt of lower respiratory infections

12 Feb 2023

Lower respiratory infections (LRIs) continue to pose a serious health problem across the globe, particularly in vulnerable areas and among children aged <5 years and adults >70 years, reveals a study.

12 Feb 2023

Ultrathin bronchoscopy boasts higher diagnostic yield for peripheral pulmonary lesions

11 Feb 2023

The diagnostic yield for peripheral pulmonary lesions is higher with ultrathin bronchoscopy compared to thin bronchoscopy, as shown in a study, noting that a radial probe endobronchial ultrasound (rEBUS) cannot be inserted through a thin bronchoscope.

11 Feb 2023

Is first-line lazertinib monotherapy a potential new SoC for EGFRm NSCLC?

10 Feb 2023 by

Patients with EGFR-mutated (EGFRm) advanced non-small cell lung cancer (NSCLC) exhibited significantly improved progression-free survival (PFS) when treated with lazertinib compared with gefitinib in the first-line setting, results of the LASER301 trial showed.

10 Feb 2023

Reduced lung function may induce hypertension

10 Feb 2023

Reduced lung function, regardless of smoking status, contributes to an increased hypertension prevalence, reports a study.

10 Feb 2023

Ultrathin bronchoscopic cryobiopsy safe, effective for lesions probe

10 Feb 2023

The feasibility of ultrathin bronchoscopic cryobiopsy has been proven recently in a study, which also demonstrates its effectiveness and safety for the diagnosis of peripheral pulmonary lesions.

10 Feb 2023

Anti-MDA5 antibody–positive dermatomyositis with anti-Ro52 ups ILD, mortality risks

09 Feb 2023

Patients with dermatomyositis (DM) who are positive for antimelanoma differentiation-associated gene 5 antibody (anti-MDA5) are more likely to have anti-Ro52 antibodies as well, and such coexistence appears to heighten the risks of rapidly progressive interstitial lung disease (ILD) and mortality, suggests a recent study.

09 Feb 2023