News &amp; Updates

In the post hoc analysis of the AURORA 1 and 2 trials, the novel calcineurin inhibitor voclosporin was effective in achieving complete renal response (CRR)* in individuals with severe lupus nephritis** (LN).

Commercial smartwatch detects low blood oxygen saturation

Compared with a medical-grade pulse oximeter, the Apple Watch Series 6 can detect reduced levels of blood oxygen saturation (SpO2) as accurately as a medical-grade pulse oximeter does, according to a recent study.

Palbociclib–bazedoxifene combo for HR+/HER2− breast cancer succeeds in early trial

Treatment with the combination of palbociclib plus bazedoxifene demonstrates clinical efficacy while having an acceptable safety profile in treatment-experienced patients with hormone receptor–positive/HER2-negative (HR+/HER2−) advanced breast cancer, according to the results of a phase Ib/II study.

14 Dec 2022

Carotid atherosclerosis ups risk of small fibre nerve dysfunction in T2D

Among patients with type 2 diabetes (T2D), the presence of carotid atherosclerosis appears to aggravate the risk of developing small fibre nerve dysfunction, a recent study has found.

14 Dec 2022

Acalabrutinib-based chemo-free triplet shows high rates of MRD-negative CR in 1L MCL study

First-line (1L) acalabrutinib in combination with lenalidomide and rituximab (ALR) has demonstrated high rates of minimal residual disease (MRD)–negative complete remission (CR) in patients with mantle cell lymphoma (MCL), including patients with TP53 mutations, in a single-arm phase II trial reported at the 64^th American Society of Hematology (ASH) Annual Meeting and Exposition.

14 Dec 2022

Maralixibat improves pruritus across all PFIC types

Treatment with maralixibat significantly reduced the severity of pruritus in children with progressive familial intrahepatic cholestasis (PFIC) in the MARCH-PFIC* study presented at The Liver Meeting 2022.

Does fMRI neurofeedback improve symptoms, cognition in children with ADHD?

Nonpharmacological treatment with functional magnetic resonance imaging neurofeedback (fMRI-NF) of the right inferior frontal cortex (rIFC) does not seem effective in improving clinical symptoms or cognition in boys with attention deficit hyperactivity disorder (ADHD), reports a recent study.

13 Dec 2022

Digital pathology with AI offers new insights into fibrosis regression in NASH

13 Dec 2022 by

Second harmonic generation/two-photon excitation fluorescence (SHG/TPEF) microscopy with artificial intelligence (AI) analyses reveals novel facets of treatment-induced fibrosis regression in nonalcoholic steatohepatitis (NASH), which are not normally captured by existing staging systems, reports a study.

Educational intervention improves cancer knowledge among community pharmacists

A recent study in Ghana has shown significant improvements of participants’ knowledge in all aspects of cancer among community pharmacists compared to the results of the preassessment study.