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Obesity, overweight up risk of complications from radical cystectomy
Body mass index is independently associated with the development of complications from radical cystectomy, reports a study. Compared to patients with normal BMI, those who are overweight and obese have a higher risk.

EMERALD updates highlight therapeutic potential of elacestrant for ER+/HER2– mBC
In the updated analysis of the phase III EMERALD trial, the next-generation oral SERD* elacestrant continued to show favourable signals for the treatment of ER+/HER2– metastatic breast cancer (mBC).

Can vitamin D ease overactive bladder, urinary incontinence symptoms in older men?
Supplementation with vitamin D does not lead to improvements in overactive bladder or urinary incontinence relative to placebo, a study has shown. However, specific use of vitamin D in men with lower 25-hydroxyvitamin D levels shows inconsistent results.

Maintenance olaparib confers survival benefit for HRD+ ovarian cancer patients
In the final overall survival (OS) analysis of the phase III PAOLA-1*/ENGOT-ov25 trial, the addition of olaparib to bevacizumab provided a survival benefit for women with newly diagnosed advanced ovarian cancer with HRD**-positive (HRD+) tumours.





