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Dupilumab cuts exacerbations, improves lung function in paediatric asthma patients with high eosinophils
In the post hoc analysis of data from the phase III LIBERTY ASTHMA VOYAGE study, the monoclonal antibody dupilumab reduced exacerbations and improved lung function in children aged between 6 and 11 years with moderate-to-severe asthma and baseline blood eosinophil count of ≥500 cells/μL.

Panitumumab plus trifluridine-tipiracil confers survival advantage in RAS wild-type MCRC
In the third-line treatment of patients with refractory RAS wild-type metastatic colorectal cancer (MCRC), use of panitumumab plus the standard-of-care trifluridine-tipiracil appears to prolong progression-free survival (PFS) when compared with trifluridine-tipiracil alone, according to data from a phase II study.

Takotsubo syndrome tied to impaired LV contractility, shortened systolic period
Patients with Takotsubo syndrome (TTS), a reversible form of heart failure with incompletely understood pathophysiology, may exhibit reduced cardiac contractility, shortened systolic period, inefficient energetics, and prolonged active relaxation but unaffected diastolic passive stiffness, a study has shown.

Herbal combination works in treatment of active ulcerative colitis
The herbal combination of curcumin plus QingDai (CurQD) appears beneficial to patients with active ulcerative colitis (UC), with a recent study showing that the combination induced clinical and biomarker remission.

In-utero exposure to poor air quality a risk factor for childhood ADHD
Children born to mothers who were exposed to polluted air while pregnant are at increased risk of childhood attention-deficit hyperactivity disorder (ADHD), according to a study presented at PAS 2023.




