News & Updates

Treatment with fostamatinib, a spleen tyrosine kinase inhibitor that targets B cells and plasma cells, is well tolerated by patients with hidradenitis suppurativa (HS), resulting in improved clinical outcomes with no serious adverse events, a study has shown.

In Singapore, poorly controlled gout appears to be common among men, Malays, and individuals with congestive cardiac failure, as reported in a study.

Use of undiluted lacosamide and levetiracetam to prevent seizures does not result in significant adverse events when administered via intravenous (IV) push over 5 min, according to a study. This approach appears to be a safe alternative form of administration to intermittent infusion.

An increase in dietary glycaemic index, glycaemic load, and amounts of starch, added sugars, refined grains, and starchy vegetables result in more weight gain in midlife, suggests a study. On the other hand, greater intake of fibre, whole grains, fruits, and nonstarchy vegetables is associated with better weight control.

A 20-year retrospective study in Hong Kong has shown that renal relapse generally occurs within the first 5 years after diagnosis of childhood-onset lupus nephritis (cLN) in Chinese patients. The risk of renal relapse is higher in those diagnosed at young age, those failing to achieve complete remission (CR) 12 months after induction therapy, and those receiving maintenance therapy other than mycophenolate mofetil (MMF).

Exposure to acid-suppressive therapy during the first year of life appear to come with a small but significant increase in the risk of fractures, according to a study.

Exposure to per- and polyfluoroalkyl substances (PFAS), dubbed “forever chemicals,” may contribute to a delay in puberty through its effects on body mass index (BMI) and sex hormones, as shown in a study.