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Anxiety and depression prevalent in primary care
The presence of coexisting clinical depression and anxiety (DA) is not uncommon in the primary care setting, particularly among younger individuals, patients with diabetes, and women, a Singapore study has shown.

Two-component nutritional strategy on par with standard approach for BP control
A two-component nutritional strategy is as effective as the established dietary intervention for blood pressure (BP) control in individuals with hypertension, results of the NUPRESS study have shown.

Exercise, Mediterranean diet remain key against MASLD
A 12-week lifestyle intervention comprising a moderate-intensity physical activity (PA) programme and a hypocaloric Mediterranean diet (MD) promoted fat removal and liver fibrosis improvement in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD), findings from the EHmet-DIA study suggest.

Obeticholic acid reduces progression to cirrhosis in patients with MASH-related fibrosis
Treatment with obeticholic acid (OCA) improves clinical outcome in patients with precirrhotic fibrosis due to metabolic dysfunction-associated steatohepatitis (MASH), with a reduction in histological progression to cirrhosis seen in those receiving the 25-mg dose, as seen in the final results of the REGENERATE study.

Resmetirom proves efficacy in NASH patients with or without MetALD
Patients with biopsy-confirmed nonalcoholic steatohepatitis (NASH) and fibrosis treated with resmetirom achieve NASH resolution with no fibrosis worsening (NR) or ≥1-stage fibrosis improvement with no worsening of the NAS score (FI), according to the results of the ongoing MAESTRO-NASH study.




