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Bladder-directed heated chemotherapy of no clear benefit in NMIBC
In patients with intermediate-risk nonmuscle-invasive bladder cancer (NMIBC), intravesical chemohyperthermia (CHT) does not translate to better cancer control than standard room-temperature chemotherapy, according to a recent phase II study HIVEC-II.

Intravesical pembrolizumab delivers antitumour activity in NMIBC
A recent first-in-human study has shown that directly applying pembrolizumab to the bladder is a safe and effective treatment option for patients with nonmuscle-invasive bladder cancer (NMIBC) who are unresponsive to bacillus Calmette-Guérin (BCG) treatment.

Tension-free vaginal tape for stress incontinence safe, effective in long term
Among women with stress urinary incontinence, the retropubic tension-free vaginal tape (TVT) retains its efficacy up to 24 years after initial placement, with adverse effects being uncommon and having a low impact on quality of life, according to a study.

Triplet therapy with ARSI, docetaxel, ADT boosts survival in mHSPC
Adding androgen receptor signaling inhibitors (ARSI) to a treatment regimen consisting of docetaxel and androgen deprivation therapy (ADT) can lead to better survival outcomes in patients with metastatic hormone-sensitive prostate cancer (mHSPC), according to a recent meta-analysis.

Chemoablative gel preferrable over surgery in adults with nonmuscle-invasive bladder cancer
UGN-102, a nonsurgical, chemoablative gel used as a primary treatment for nonmuscle-invasive bladder cancer (NMIBC), is more patient-centred than standard treatments, according to a recent study.



