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Long-term benefits with molnupiravir modest at best in COVID-19 treatment
The antiviral molnupiravir confers continued but modest benefits in terms of reducing COVID-19–related symptoms up to 6 months after the index infection in a vaccinated population, according to a secondary analysis of the PANORAMIC trial.

Surgery, mechanical aspiration do not prevent death in tricuspid valve infective endocarditis
Valve surgery or percutaneous mechanical aspiration, in combination with medical therapy, fall short of providing survival benefits to patients with isolated tricuspid valve infective endocarditis, results of a study have shown. However, addiction medicine consultation appears to be protective against the risk of death at 1 year in this population.

Laughter is ‘best’ medicine for dry eye disease
A recent study has found that laughing can be as effective as artificial tears (ie, 0.1% sodium hyaluronic acid eye drop) in relieving ocular surface discomfort in patients with dry eye disease (DED) with limited corneal staining.

Maternity leave extension in HK lowers postnatal depression rate by 22 percent
Paid maternity leave extension to 14 weeks in Hong Kong led to a 22 percent reduction in the rate of probable postnatal depression, researchers from the University of Hong Kong (HKU) and the National University of Singapore (NUS) have reported.

Long-term freedom from insulin may be achieved with duodenal electroporation plus semaglutide
The combination of re-cellularization via electroporation therapy (ReCET) plus semaglutide appears to improve glucose control and metabolic health and eliminate the need for insulin therapy in most patients with type 2 diabetes (T2D), with the effects maintained up to 2 years, according to the follow-up data from the single-arm, dose-finding, first-in-human EMINENT trial.




