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Carriers of the CYP2C19 allele are at greater risk of voriconazole-induced thrombocytopenia and cholestasis, reports a Japan study.
Urinary incontinence (UI) does not appear to affect the performance of children in school, reports a recent study.
Alanine aminotransferase (ALT) appears to be a useful primary screening measure to identify early signs of fibrosis, such as increased liver stiffness, in children with overweight or obesity and additional risk factors, according to a study.
Hypertension in children and adolescents appears to be associated with heightened long-term risk of major adverse kidney events (MAKEs), according to a large retrospective study.
A short-course antibiotic treatment for children with community-acquired pneumonia (CAP) demonstrates effectiveness similar to the long-course regimen but with fewer serious adverse events (AEs), reports a study.
Treatment with either ceftazidime-avibactam (CAZ/AVI) or ceftolozane-tazobactam (C/T) is well tolerated and effective in children infected with Gram-negative pathogens resistant to carbapenems, a recent study has shown.
Influenza vaccination in pregnant women, especially during the second or third trimester, cuts the risk of infection in infants, as shown in a study.
Acute respiratory infections (ARIs) are associated with various symptoms across different age groups, according to a Korea study.
In adolescents with homozygous familial hypercholesterolemia (HoFH), treatment with inclisiran appears to be safe and efficacious for reducing low-density lipoprotein cholesterol (LDL-C) levels, according to the results of the first part of the phase III ORION-13* trial.
Exposure to biologics for inflammatory bowel disease (IBD) in utero or during breastfeeding does not appear to impair psychomotor development in infants, according to a study.