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Novel EGFR-TKI drug shows favourable antitumour activity in NSCLC
Treatment with the novel EGFR tyrosine kinase inhibitors (EGFR-TKI) abivertinib at 300 mg twice a day appears to be effective in patients with EGFR T790M-positive nonsmall cell lung cancer (NSCLC), while having manageable side effects, according to the results of a phase II trial.

Fulvestrant–sapanisertib combo shows modest benefit in advanced, metastatic breast cancer
Treatment with the combination of fulvestrant plus sapanisertib yields a numerical increase in progression-free survival in patients with ER-positive, HER2-negative advanced or metastatic breast cancer as compared with the use of fulvestrant alone, according to the results of a phase II trial. However, the combination is associated with increased toxicity.

Respiratory-gated PET-CT improves liver tumour imaging
A prospective clinical study conducted by the Hong Kong Baptist Hospital in collaboration with the Hong Kong Polytechnic University has demonstrated the feasibility of implementing respiratory-gated PET-CT for liver malignancies with improved image quality compared with ungated scans.

Olaparib-abiraterone combo improves PFS in mCRPC
The combination of olaparib and abiraterone in the first-line setting improved radiographic progression-free survival (rPFS) in patients with metastatic castration-resistant prostate cancer (mCRPC), results of the phase III PROpel trial showed.




