News &amp; Updates

Supplementation with palmitoleic acid (POA) 500 or 1,000 mg/day does not appear to substantially reduce high-sensitivity C-reactive protein (hs-CRP) or change other biomarkers in adults relative to placebo, reports a study.

Nirsevimab cuts RSV burden in newborns

10 Dec 2025 by

A retrospective study from Italy shows an association between nirsevimab prophylaxis and a lower risk of respiratory syncytial virus (RSV) hospitalizations and a milder disease course.

Engasertib shows promise in hereditary haemorrhagic telangiectasia

In the treatment of patients with hereditary haemorrhagic telangiectasia (HHT), use of the novel allosteric, selective AKT inhibitor engasertib appears to be safe and reduce the frequency and duration of epistaxis, according to a proof-of-concept study.

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

Plasma phosphorylated tau 217 (p-tau217) can identify pathological changes characteristic of Alzheimer’s disease (AD) in older adults without cognitive impairment, according to a meta-analysis.

Atherosclerosis in vascular beds tied to lower risk of fast aneurysm growth

A recent study has found an association between atherosclerosis in vascular beds outside of the aorta and a reduced risk of fast aneurysm growth.

Is it safe to take NSAIDs when using oral anticoagulants?

The use of oral anticoagulants (OACs) with NSAIDs results in clinical outcomes like those of OAC monotherapy, a study has shown.

Diastolic hypotensive episodes predict MACE, rehospitalization in stable HF patients

In patients with stable heart failure (HF), a diastolic hypotension episode (diastolic blood pressure [DBP] <60 mm Hg) is associated with hemodynamic vulnerability and with a higher risk of adverse outcomes, particularly HF rehospitalization, a study has shown.

Plug- vs suture-based devices: Which is better for large-bore arterial access closure?

A systematic review and meta-analysis that included 23 studies shows similar safety and efficacy profiles between plug-based vascular closure devices (P-VCDs) and suture-based VCDs (S-VCDs) in large-bore arterial access closure, but the former appears to have an edge over the latter in terms of bleeding events and hospital stay in some of the studies.

Tobevibart–elebsiran combo demonstrates therapeutic potential against hepatitis D

Patients with chronic hepatitis D virus (HDV) infection appear to respond to treatment with the combination of tobevibart plus elebsiran, according to the phase II, open-label SOLSTICE trial.

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker

Researchers from the School of Life Sciences and the Gerald Choa Neuroscience Institute at the Chinese University of Hong Kong (CUHK) have found that estradiol (E2) to progesterone (P4) (E2:P4) imbalance during perimenopause likely increases the risk of Alzheimer’s disease (AD) and AD-related dementia in women via oestrogen-related receptor alpha (ERRα) dysfunction.