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Initiating antiretroviral therapy (ART) within 48 hours of life for infants born with HIV can lead to sustained viral suppression, as reflected by reduced HIV reservoirs by age 2 years, which suggests the possibility of an ART-free remission.
Wearing soft contact lenses with extended depth of focus reduces axial elongation and, in turn, delays the progression of myopia in children when compared with using distance single-vision spectacles, as shown in a study.
In Singapore, about one in six children and young persons (CYPs) developed long COVID, with persistence of ≥1 symptoms 3 months after an acute COVID-19 infection, a survey study suggests.
The risk of colectomy in paediatric onset ulcerative colitis (UC) has significantly decreased at the population level along with an increase in the use of immunosuppressants and antitumour necrosis factor (anti-TNF), reports a study.
Maternal cannabis use during pregnancy appears to contribute to increased risk of adverse neonatal health outcomes, including low birth weight (LBW) and small for gestational age (SGA), as reported in a study.
Treatment with flexible ureteroscopy (FE) results in a significantly higher stone-free rate than shock wave lithotripsy (SWL) in children with renal stones, reports a study. No difference is seen in complication rate or fluoroscopy exposure time between groups, but operative times and hospital stay are longer with FU.
Treatment with dupilumab reduces the use of systemic corticosteroids (SCS) in children with moderate-to-severe asthma, regardless of exacerbation history, according to a post hoc analysis of the VOYAGE and EXCURSION trials presented at APSR 2023.
The respiratory system is the main target of human rhinovirus/enterovirus (HRV/EV) infections, which show a clinical course with low mortality rates, reveals a study.
Children who test positive for human rhinovirus/enterovirus (HRV/EV) require close monitoring by clinicians, given possible clinical outcomes that are either similar or worse than known highly pathogenic viruses, suggests a recent study.
Twelve-month treatment with zoledronate significantly increases bone mineral density (BMD) Z-scores without affecting growth in nonambulant children with cerebral palsy (CP), reports a study. However, side effects of the first dose are common.
