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FTD/TPI-bevacizumab combo a new SoC for metastatic CRC?
A combination of trifluridine/tipiracil (FTD/TPI) and bevacizumab provided significant survival benefit when used as third-line treatment for refractory metastatic colorectal cancer (CRC) than FTD/TPI alone, findings from the phase III SUNLIGHT study suggest.

Dynapenia ups risks of falls, fractures in women with obesity
Reduced muscle strength (dynapenia) is associated with a higher risk of leg and ankle fractures in women with obesity, as shown in a study. Dynapenia also negates the protective effects of obesity on fractures of the wrist, arm, hip, spine, and other bones, thus increasing the risk of falls.

Prophylactic aflibercept reduces vision-threatening complications without gains in visual acuity
Treatment with intravitreal aflibercept in patients with nonproliferative diabetic retinopathy but without centre-involved diabetic macular edema appears to slow disease progression and reduce the risk of developing vision-threatening complications but fall short of improving visual acuity, according to a study.

Outpatient oritavancin bests inpatient SoC in acute uncomplicated cellulitis
Outpatient oritavancin therapy appears to be more effective than inpatient standard-of-care (SoC) in reducing 30-day hospital readmissions or admissions among individuals with acute uncomplicated cellulitis, a recent study has shown.




