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Add-on fluvoxamine of no benefit in mild-to-moderate COVID-19

07 Jul 2023

In the treatment of patients with mild-to-moderate COVID-19, adding fluvoxamine to favipiravir does not appear to prevent disease progression or improve certain outcomes, according to the results of an open-label study.

07 Jul 2023

Preoperative HIIT beneficial to individuals undergoing major surgery

06 Jul 2023

Patients scheduled to undergo major surgery appear to improve their cardiorespiratory fitness (CRF) with a preoperative high-intensity interval training (HIIT) program, which in turn reduces postoperative complications, according to a study.

06 Jul 2023

Healthy diet tied to improved physical fitness

03 Jul 2023 by

A recent study found an association between a healthy diet and greater physical fitness in middle-aged adults.

03 Jul 2023

COVID outcomes worse in polluted cities

01 Jul 2023 by

More evidence suggests that people exposed to more air pollution during the pandemic are at greater risk for COVID-19 infection, hospitalization, and death, but the exact mechanism behind the link is unknown.

01 Jul 2023

DOACs as good as LMWH for recurrent VTE prevention in cancer patients

29 Jun 2023

For patients with cancer who have recurrent venous thromboembolism (VTE), direct oral anticoagulants (DOACs) compare favourably with low-molecular-weight heparin (LMWH) in terms of recurrence prevention, according to a study.

29 Jun 2023

Hypertension tied to weakened ventilatory efficiency

27 Jun 2023

Hypertensive individuals without a diagnosis of heart failure appear to have impaired ventilatory efficiency, which reflects an abnormal physiological response to exercise, according to a study.

27 Jun 2023

Gliosis may explain depressive or cognitive symptoms after COVID

22 Jun 2023 by

Patients with persistent depressive or cognitive symptoms after an acute SARS-CoV-2 infection have elevated gliosis – a secondary event to brain injury – and inflammation as shown in a case-control study.

22 Jun 2023

COVID-19 oral antivirals reduce hospitalization and inpatient progression in nursing home residents

21 Jun 2023 by

A territory-wide, retrospective cohort study in Hong Kong has shown that molnupiravir and nirmatrelvir/ritonavir are effective in reducing the risks of hospitalization and inpatient disease progression among older patients residing in nursing homes.

21 Jun 2023

Updated CodeBreak 200 analyses boost sotorasib role in KRASG12C-mutant NSCLC

19 Jun 2023 by

In the PRO analyses of the phase III CodeBreak 200 trial, the first-in-class KRAS^G12C inhibitor sotorasib improved quality of life (QoL) of patients with pretreated KRAS^G12C-mutated advanced non-small-cell lung cancer (NSCLC) compared with docetaxel.

19 Jun 2023

Hint of benefit with antifibrotic treatment seen for interstitial lung disease

16 Jun 2023

Antifibrotic treatment appears to put brakes on the decline of lung function, as evidenced by forced vital capacity (FVC) measurements, in patients with interstitial lung disease (ILD) related to connective tissue disease (CTD) or rheumatoid arthritis (RA), according to a study.