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Taking sublingual cyclobenzaprine (TNX-102 SL) at bedtime relieves fibromyalgia symptoms and improves function, a phase III study suggests.
For Chinese women with epilepsy, periconceptional folic acid intake helps minimize the incidence of seizures during pregnancy and reduce the risk of pregnancy loss, as shown in a study.
Patients with hepatocellular carcinoma (HCC) weighing <55 kg who initiate a full dose of lenvatinib tend to lose weight or discontinue treatment, reports a study.
A systematic review and meta-analysis support the safety of paracetamol on child neurodevelopment when used appropriately during pregnancy.
Treatment with berberine in diabetes-free individuals with obesity and metabolic dysfunction–associated steatotic liver disease (MASLD) is safe but falls short of reducing visceral adipose tissue (VAT) and liver fat content, as reported in a study.
Aprocitentan appears beneficial in the treatment of patients with both resistant hypertension and chronic kidney disease (CKD), having been shown to improve blood pressure control and reduce urine albumin-to-creatinine ratio (UACR) when added to standardized background antihypertensive therapy.
Initiation of postexposure prophylaxis for HIV and completion rates in paediatric sexual assault victims can be improved by implementing a structured care system that involves multidisciplinary collaboration, pioneered by paediatric infectious diseases, suggests a Turkey study.
Patients with systemic autoimmune inflammatory diseases—including systemic sclerosis, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA)—face an increased risk of heart failure (HF), as suggested in a retrospective study.
A study in a UK hospital has found contamination for 5-fluorouracil (5FU) and cyclophosphamide (CP) on the products compounded in the isolators, which then extends towards the administration department, affecting surfaces in between.
Treatment with spironolactone at low doses helps improve blood pressure control in patients with primary aldosteronism, with the added benefit of reduced adverse effects, as shown in a retrospective study.
