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Abdominal fat tied to reduced brain function in middle-aged men at high dementia risk
Higher abdominal fat, particularly around the pancreas, appears to contribute to lower cognition and brain volumes among middle-aged men at high risk of Alzheimer’s dementia, reports a study. This suggests a possible sex-specific link between distinct abdominal fat and brain health.
Body fat percentage changes predict diabetes remission after bariatric surgery
Changes in body fat percentage (BFP) are significantly associated with diabetes remission after bariatric surgery, suggests a study, noting that baseline fat-free mass index (FFMI) is vital for BFP changes.
Lung cancer screening tied to reduced mortality
In an observational study conducted in Poland, individuals who participated in a low-dose computed tomography (LDCT) lung cancer screening programme had a reduction in all-cause mortality compared with a matched control group extracted from a general Polish cohort.
NCHT improves PFS in locally advanced prostate cancer
Neoadjuvant chemohormonal therapy (NCHT) plus radical prostatectomy (RP) confers significant biochemical progression-free survival (bPFS) benefits relative to neoadjuvant hormonal therapy (NHT) plus RP on patients with high-risk, locally advanced prostate cancer, reports a study.
MIRASOL PRO data boost mirvetuximab soravtansine potential in FRα-positive ovarian cancer
Patient-reported outcomes (PROs) from the phase III MIRASOL trial underpin the potential of the antibody drug conjugate mirvetuximab soravtansine (MIRV) to improve health-related quality of life (HRQoL) in women with folate receptor-alpha positive platinum-resistant ovarian cancer (FRα-positive PROC) as opposed to investigator’s choice of chemotherapy.