News &amp; Updates

Does sacubitril-valsartan plus spironolactone induce ADRs?

Treatment with the combination of sacubitril-valsartan plus spironolactone during hospitalization for acute decompensated heart failure (ADHF) does not lead to a substantially higher incidence of adverse drug reactions (ADRs), a study has shown.

Does sacubitril-valsartan plus spironolactone induce ADRs?

Abnormal body weight in adolescence a risk factor for infertility in Asian women

Underweight or obesity during adolescence may contribute to unexplained infertility later in life, as suggested in a large study involving Japanese women.

Abnormal body weight in adolescence a risk factor for infertility in Asian women

Baricitinib plus phototherapy shows potential against extensive vitiligo

Treatment with the combination of the small molecule Janus kinase 1/2 inhibitor baricitinib plus phototherapy may help reduce disease activity and induce repigmentation in adults with extensive and active nonsegmental vitiligo, according to the results of a phase II study.

Baricitinib plus phototherapy shows potential against extensive vitiligo

Antipsychotic adherence helps keep lid on suicidal behaviour

01 Feb 2025 by

Ensuring antipsychotic medication use as prescribed may be crucial for reducing the risk of suicidality among patients with schizophrenia, according to a study.

Antipsychotic adherence helps keep lid on suicidal behaviour

Clozapine tied to haematological malignancy in schizophrenia

01 Feb 2025 by

The use of clozapine appears to slightly increase the risk of haematological malignancy (HM) among patients with schizophrenia compared with olanzapine use, suggests a study.

Clozapine tied to haematological malignancy in schizophrenia

01 Feb 2025

Laparoscopic noninferior to open surgery for low rectal cancer

The disease-free survival outcome in patients with low rectal cancer who receive laparoscopic surgery compares favourably with that in those who receive open surgery, according to a study.

Laparoscopic noninferior to open surgery for low rectal cancer

Prourokinase does not improve functional outcomes in mild ischaemic stroke

In the treatment of patients with mild ischaemic stroke, prourokinase is not necessarily better than standard of care in terms of improving functional outcomes, although both have a similar safety profile, according to a study.

Prourokinase does not improve functional outcomes in mild ischaemic stroke

Electrospun fibre patch to simplify psoriasis treatment

31 Jan 2025 by

A new patch that adheres to the skin and delivers two active ingredients holds promise in the treatment of psoriasis, reducing the need to apply topical medications to once a day and potentially improving adherence.

Electrospun fibre patch to simplify psoriasis treatment

Seizure history does not elevate risk of cefepime-induced neurotoxicity

Patients with a history of seizures do not appear to be at an increased risk of cefepime-induced neurotoxicity (CIN), according to a study.

Seizure history does not elevate risk of cefepime-induced neurotoxicity