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CPET a useful cardiovascular risk assessment tool for patients undergoing cancer surgery
For patients undergoing surgery for oesophageal and gastric cancer, cardiopulmonary exercise testing (CPET) appears to be a reliable predictor of major cardiovascular complications, as reported in a study.
Ribociclib–binimetinib combo safe, effective in NRAS-mutant melanoma
Treatment with the combination of ribociclib plus binimetinib appears to be well tolerated and delivers modest clinical activity in patients with locally advanced or metastatic melanoma harbouring NRAS mutation, according to the results of a phase Ib/II study.
Early mortality explains colorectal cancer survival gap between older, young patients
In patients with colorectal cancer (CRC), the survival gap between older and younger patient can largely be attributed to deaths during the first year after resection, a recent study has found.
Weekly dose-dense CT does not confer survival benefit for ovarian cancer patients
In the final analysis of the phase III ICON8* study, a weekly dose-dense chemotherapy (CT) regimen comprising paclitaxel and carboplatin did not improve survival outcomes in women with epithelial ovarian cancer** compared with the standard first-line (1L) paclitaxel-carboplatin regimen given once every 3 weeks (Q3W).