News & Updates

In the real-world treatment of Asian patients with type 2 diabetes mellitus (T2DM), the blood glucose-lowering benefit following oral antidiabetic drug (OAD) dose escalation is lesser than what has been reported in clinical trials, according to a study from Singapore.

In individuals with progressive locally advanced or metastatic radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC), the VEGFR-2* inhibitor apatinib demonstrated significant clinical benefits in terms of progression-free survival (PFS) and overall survival (OS), with a manageable safety profile, findings from the phase III REALITY trial suggest.

Targeted next-generation sequencing (NGS) appears to be useful for pinpointing causal variants in patients with suspected monogenic diabetes (MD), broadening the spectrum of new pathogenic variants and updating knowledge of the clinical features of patients with various forms of MD, according to a recent study.

Vitamin B12 concentrations in type 2 diabetes mellitus (T2DM) patients are linked to the incidence of insomnia and help pinpoint those who are likely to develop the condition according to a study.

In the management of women with polycystic ovary syndrome (PCOS), metformin at various therapeutic doses appears to reduce body weight, body mass index, and waist circumference when compared with placebo, sitagliptin, and acarbose, according to the results of a meta-analysis. On the other hand, pioglitazone and rosiglitazone contribute to an increase in all three outcomes.