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Chemotherapy plus ICI treatment ups VTE risk in cancer patients
Combination treatment with immune checkpoint inhibitors (ICI) and chemotherapy is associated with a higher risk of venous thromboembolic events (VTE) in adult cancer patients, reveals a study. In addition, a similar VTE disease course is seen after ICI exposure, irrespective of other immune-related adverse events (irAEs).
Response to therapy higher in clinical trial than real-world RCC patients
Among patients with metastatic renal cell carcinoma (RCC) who have received first-line therapies, complete response rates are lower in the real-world population than in the clinical trial population, reports a recent study. Complete response predicts a favourable overall survival.
SC trastuzumab cost-saving for HER2-positive breast cancer in Hong Kong
A cost minimization analysis based on a literature review and Hong Kong data suggests that using subcutaneous (CS) instead of intravenous (IV) trastuzumab for HER2-positive breast cancer (BC) patients can offer an annual saving of more than USD 8.3 million to the Hong Kong healthcare system.
Frequent aspirin use protects against ovarian cancer even in women with genetic predisposition
Genetic susceptibility to ovarian cancer does not appear to modify the protective association between frequent aspirin use and the risk of developing the cancer, as shown in a study.