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Which factors shape decisions to withdraw life support in stroke patients?
The decision to withdraw life-sustaining therapy (WLST) among acute hospitalized stroke patients is determined by several factors, including age, race, level of consciousness, state region, insurance status, ambulation status at baseline, and stroke centre type, suggests a study presented at ISC 2023.
Statin therapy reduces major vascular events after stroke
Treatment with statin results in a decrease in major vascular events following acute ischaemic stroke, even in patients with low or well-controlled low-density lipoprotein cholesterol (LDL-C), as shown in a study presented at ISC 2023.
DOACs, VKAs show similar efficacy, safety for VTE in octogenarians
In an international multi-database cohort study, direct oral anticoagulants (DOACs) demonstrated comparable efficacy and safety with vitamin K antagonists (VKAs) for octogenarians with venous thromboembolism (VTE).
Diet, physical activity help lower cardiometabolic disease risk
Behavioural weight-loss interventions, such as diet alone and diet plus physical activity (PA), induce a beneficial change in biomarkers of insulin resistance and cardiometabolic health in adults with overweight or obesity, reports a study. However, no additional benefit has been observed with the addition of moderate-intensity PA to a diet-only intervention.
Adipose tissue–targeted nanoparticles may improve treatment of obesity and atherosclerosis
Researchers from the University of Hong Kong (HKU) have developed a nanoparticle-based targeted drug delivery system that selectively transports thyroid hormone (TH) to adipose tissue, which may improve treatment of obesity and its related cardiometabolic complications by overcoming serious adverse events (AEs) associated with systematic TH administration.