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Treatment with budesonide shows better clinical remission rates and fewer adverse events (AEs) than mesalamine in patients with microscopic colitis (MC), reveals a study.
In the treatment of patients with aspiration pneumonia, ampicillin–sulbactam helps reduce in-hospital mortality and prevent Clostridioides difficile infection compared with cephalosporins, according to a study from Japan.
Women exposed to clomiphene citrate (CC) have fourfold greater odds of becoming pregnant with multiples, and this seems to come with adverse perinatal outcomes, as shown in a French cohort study.
For adult patients with type 2 diabetes (T2D) who are naïve to insulin, a once-weekly fixed-dose efsitora regimen is noninferior to once-daily glargine at reducing blood glucose levels, according to the phase III treat-to-target QWINT-1 trial.
For individuals with long COVID, treatment with nirmatrelvir plus ritonavir does not appear to yield improvements in health outcomes when compared with ritonavir alone, according to a phase II study.
Two large prospective cohorts show no evidence of an association between the use of oral contraceptives and the risk of liver cancer.
Treatment with 0.04% atropine appears to improve myopia control in children and teens compared with 0.01% atropine or orthokeratology, despite a higher incidence of photophobia, according to a study.
In the treatment of patients with type 2 diabetes, sulfonylureas pose an increased risk of major adverse cardiovascular events (MACE) compared with dipeptidyl peptidase 4 inhibitors (DPP4is), according to a study.
Treatment with bimekizumab showed sustained efficacy for up to 3 years in patients with nonradiographic (nr) and radiographic (r) axial spondyloarthritis (axSpA), based on a pooled analysis of the two phase III studies (BE MOBILE 1 and 2) and combined open-label extension (OLE) study presented at EULAR 2025.
Older patients with cancer are unusually susceptible to polypharmacy, as well as potentially inappropriate medications and potential drug-drug interactions, reveals a study.
