News & Updates

Pregnant women with higher adherence to a Mediterranean‐style diet are at lower risk of pre-eclampsia, with the benefit observed among Black and White women, a study has found.

Progression-free survival (PFS) is significantly longer with intraperitoneal (IP) over intravenous (IV) carboplatin, when combined with dose-dense paclitaxel, in patients with ovarian, fallopian tube, or primary peritoneal cancer, regardless of residual tumour size after initial surgery, according to the phase III iPocc* trial presented at SGO 2022.

Actively treating even mild hypertension to a target blood pressure (BP) of <140/90 mm Hg in pregnant women significantly lowers the risk of adverse pregnancy outcomes without apparent harm to the foetus compared with a strategy of reserving treatment to only when hypertension becomes severe (≥160/105 mm Hg), according to the CHAP* study presented at ACC 2022.

The humanized IgG4 monoclonal antibody tislelizumab was clinically active in women with gynaecologic microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) solid tumours, and was generally well-tolerated with no new safety signals, according to a subgroup analysis of the phase II RATIONALE 209 study presented at SGO 2022.

The first-in-class antibody-drug conjugate mirvetuximab soravtansine (MIRV) shows promising anti-tumour activity in previously treated patients with platinum-resistant ovarian cancer who express high levels of folate receptor alpha (FRα), according to the SORAYA study presented at SGO 2022.