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T2D risk elevated in thyroid cancer patients after thyroidectomy
Development of type 2 diabetes (T2D) is more likely to occur among patients with thyroid cancer who underwent thyroidectomy than matched controls, a Korea study has shown. In addition, a U-shaped dose-dependent relationship exists between the levothyroxine dosage and T2D risk.

Corticosteroids up incidence of adverse events, readmissions in severe COPD
A single-institution study does not recommend the prescription of systemic corticosteroids for the treatment of severe acute exacerbation of chronic obstructive pulmonary disease (AECOPD) as this might result in an increased incidence of adverse effects and readmissions.

T2D: Risk of CV and all-cause mortality lower with SGLT2 vs DPP-4 inhibitors
A real-world propensity score-matched study in Hong Kong finds that, compared with use of dipeptidyl peptidase-4 (DPP-4) inhibitors, use of sodium-glucose cotransporter 2 (SGLT2) inhibitors in type 2 diabetes (T2D) patients is associated with lower risk of incident atrial fibrillation (AF), stroke/transient ischaemic attack (TIA), and cardiovascular (CV) and all-cause mortality.

Niraparib-abiraterone-prednisone combo improves multiple outcomes in HRR+ mCRPC
In patients with metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene alterations*, combining niraparib with abiraterone acetate plus prednisone (AAP) in the first-line setting improved radiographic progression-free survival (rPFS) and other outcomes, results of the phase III MAGNITUDE study showed.





