Prostatic cancer, premenopausal breast cancerAdult 3.75 mg SC once every 4 wk. EndometriosisAdult 3.75 mg SC once every 4 wk. <50 kg 1.88 mg. Initial dose shall be made on the 1st-5th day after the start of menstrual period. Uterine myomaAdult 1.88 mg SC once every 4 wk. Heavy wt patient or those w/ markedly enlarged uterus 3.75 mg. Initial dose should be made on the 1st-5th day after the start of menstrual period. Central precocious puberty 30 mcg/kg SC once every 4 wk, max: 90 mcg/kg.
Renal disorder due to spinal cord compression or urethremphraxis. Submucous myoma. Prostate cancer patients w/ vertebral metastasis. Women w/ high risk in metabolic bone disease.
Adverse Reactions
Anaphylactic symptoms. Women Transient aggravation of pelvic pain, dysmenorrhea. Hot flushes, vag dryness, decreased libido, dyspareunia. Depression. Men Transient aggravation of bone pain, ureteral obstruction or spinal cord compression. Hot flushes, impotence, decrease in testes size, nausea, vomiting, edema of lower limbs, general pain. Depression.
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