Discontinue in the event of a missed miscarriage; in case of suspected MI, cerebrovascular disorders, arterial thromboembolism or VTE, thrombophlebitis or retinal thrombosis; if symptoms of depression worsens. Not indicated in threatened miscarriage. Carefully observe patients w/ epilepsy, migraine, asthma, cardiac or renal dysfunction, or diabetes. Patients w/ hormone-sensitive conditions (eg, 2nd half of menstrual cycle & pregnancy). Increased anxiety, moodiness & sensibility to seizures in abrupt progesterone discontinuation. Use rectally if barrier methods of contraception are used or if patients suffer from vag infection (especially moniliasis) or recurrent cystitis or have recently given birth. Use vaginally if patients suffer from colitis or fecal incontinence. Hepatic dysfunction. Not to be used during pregnancy & lactation.
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